Cognitive Behavioral Therapy (CBT) is grounded in psychological and neuroscientific research, demonstrating its effectiveness in treating a range of mental health conditions. At its core, CBT is based on the cognitive model, which posits that distorted or maladaptive thinking patterns influence emotions and behaviors. Neuroimaging studies have shown that CBT can create measurable changes in brain activity, particularly in the prefrontal cortex and amygdala, areas associated with emotional regulation and threat response. By teaching individuals to identify and challenge cognitive distortions, CBT helps rewire neural pathways, promoting more adaptive thinking and reducing symptoms of anxiety, depression, and other disorders. Additionally, research indicates that CBT strengthens connections between the prefrontal cortex and the limbic system, improving emotional regulation and decision-making. Its structured, goal-oriented approach is supported by clinical trials, which consistently demonstrate its efficacy in both short-term symptom relief and long-term mental health improvement..